Description: Das Projekt "In vitro reactivity of fine and ultrafine particles" wird/wurde gefördert durch: Universite de Lausanne, Institut universitaire romand de Sante au Travail. Es wird/wurde ausgeführt durch: Universite de Lausanne, Institut universitaire romand de Sante au Travail.Toxicity of particulates may be due to the reactivity of their surface when entering in contact with cells. Among other, their potential to generate reactive oxygen species seems to be very important. This work intends to use a simple method in order to determine the ability of some particles (ultrafine TiO2, crocidolite, diesel SRM 1650 and particles from real occupation situations) to catalyse the oxygen reduction by ascorbic acid. The results obtained indicated that: It is possible to detect such reaction with simple equipment (specific oxygen electrode) In the experimental conditions, diesel SRM 1650 reacts about 10 times faster than crocidolite and that ultrafine TiO2 didnt showed any reactivity. Particles sampled in a bus depot indicated a very high reactivity. Heavy metals (Fe, Cu) could be potential important elements to explain this reactivity. Experimental improvement has to be done mainly for getting a particulate suspension without artefacts.
SupportProgram
Origin: /Bund/UBA/UFORDAT
Tags: Dieselkraftstoff ? Titandioxid ? Ascorbinsäure ? Sauerstoff ? Schwermetall ? Ultrafeinstaub ? Asbest ? Omnibus ? Suspension ? Partikelminderung ? Zelle ? Arbeit ? Partikel ? Art [Spezies] ? Elektrode ? Erlass [Recht] ? Muskelarbeit ?
License: cc-by-nc-nd/4.0
Language: Englisch/English
Time ranges: 2007-01-01 - 2010-12-31
Webseite zum Förderprojekt
http://www.i-s-t.ch/ (Webseite)Accessed 1 times.