Description: List of granted and currently running projects by external researchers (Status: 6 November 2017) Principal investigator Organization D. Richardson Department of Epidemiology, University of North Carolina, Chapel Hill, USA Outline of the Project Title of the projectStart of the project PUMA – Pooled Uranium Miners AnalysisMay 2016 The project PUMA (Pooled Uranium Miners Analysis) is a worldwide pooling project, including miner cohorts from the EU, US and Canada. It involves analyses of available data that have been collected for the purposes of prior epidemiological studies. The combined study cohort encompasses more than 100,000 miners. The proposed collaborative pooling of data will yield results for cause-specific mortality risk analyses with greater precision than those obtained in any single cohort included in the collaboration. In detail the following specific aims will be addressed: Comparison of causes of deaths in miners with the general population. Radon exposure and risk of solid cancers other than lung. Radon exposure and risk of haematologic cancers. Radon exposure and risk of circulatory diseases. Radon exposure and risk of respiratory diseases. Lung cancer risk at low exposure/exposure rates of radon. Temporal effect modifiers for radon-associated risk of lung cancer. Lung cancer and combined effects of radon and smoking. Health effects of gamma exposures in uranium miners. Assessment of lifetime risks associated with radon exposure. Involved institutes: BfS - Federal Office for Radiation Protection, Germany; CCO - Cancer Care Ontario, Canada; IRSN - Institute for Radiation Protection and Nuclear Safety, France; NIOSH - National Institute for Occupational Safety and Health, USA; SURO - Radiation Protection Institute, Czech Republic; UNC - University of North Carolina, USA; USC - University of Southern California, USA; UCSF - University of California, San Francisco, USA Principal investigatorOrganizationTitle of the projectStart of the project M. MöhnerFederal Institute for Occupational Safety and Health (BAuA), BerlinNested case-control study on the risk of acute myocardial infarction in uranium miners1. September 2015 Outline of the Project In a nested case-control study based on data from the German Wismut cohort of uranium miners the relationship between typical exposures in uranium mines and the risk for acute myocardial infarction (AMI) will be investigated, taking into account information on potential confounders. Principal investigatorOrganizationTitle of the projectStart of the project L. ZablotskaUniversity of California, San FranciscoPooled analysis of mortality among German and Canadian uranium millers and processors1. January 2014 Outline of the Project The project aims to examine radiation-related risks of mortality from site specific-cancers, with special attention to cancers of the lung and bronchi, leukemia and lymphoma, bone, liver and kidney cancers, as well as non- malignant respiratory, renal and cardiovascular diseases in the pooled analysis of Port Hope and Wismut uranium milling and processing workers (n=6,806), separately and together for RDP internal exposures and γ-ray external exposures. Furthermore it should determine the effects of exposures to radium and silica dust on the radiation-related risks of mortality in the pooled analysis of Port Hope and Wismut uranium milling and processing workers. The project should also investigate radiation-related risks of mortality in the exploratory analysis of a cohort of women involved in uranium milling and processing at Port Hope and Wismut (355 and 270 workers, respectively). Principal investigatorOrganizationTitle of the project H. KüchenhoffLudwig-Maximilians- Universität München, Department of Statistics, MunichThe exposure-lag-response 1. March 2016 association between occupational radon exposure and lung cancer mortality Outline of the Project Start of the project The aim of this project is to apply the DLNM (distributed lag non-linear models) framework to the German uranium miners cohort (Wismut cohort) to derive estimates of exposure-lag-response associations between occupational radon exposure and lung cancer mortality. The specific objectives are to characterize the exposure-lag-response associations between occupational radon exposure and lung cancer, assessing the shape of the exposure-response relationship and its lag structure. Furthermore, it aims to extend the results obtained with traditional approaches (previously adopted to model the lung cancer risk of time varying exposure to radon and applied to the Wismut cohort) and to compare the results with those previously obtained using the data from the CPUM (Colorado Plateau Uranium Miners) cohort. Additionally, the DLNM methodology will be extended to excess relative risk (ERR) models and the results will be compared with the current implementation in log-linear models. Project in collaboration with C. Kaiser, Helmholtz Zentrum München, and A. Gasparrini, London School of Hygiene and Tropical Medicine. Principal investigatorOrganizationTitle of the project C. KaiserHelmholtz Zentrum München, Institute of Radiation Protection GermanyThe exposure-lag-response 1. March 2016 association between occupational radon exposure and lung cancer mortality Outline of the Project Start of the project Project in collaboration with H. Küchenhoff, LMU München, and A. Gasparrini, London School of Hygiene and Tropical Medicine. See project description above.
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Tags: London ? München ? Radon ? Siliziumdioxid ? Colorado ? Kalifornien ? North Carolina ? Bismut ? Katze ? Kombinationswirkung ? Staubbelastung ? Uran ? Akute Exposition ? Frankreich ? Kanada ? USA ? Tschechische Republik ? Gesundheitliche Auswirkungen ? Epidemiologische Studie ? Bronchien ? Expositionsdauer ? Knochen ? Leukämie ? Lungenkrebs ? Radium ? Strahlenschutz ? Hafen ? Fallkontrollstudie ? Risikoanalyse ? Atemwegserkrankung ? Arbeitsschutz ? Krebserkrankung ? Krebsrisiko ? Mortalität ? Herz-Kreislauf-Erkrankung ? Studie ? Daten ? Schule ? Expositionsanalyse ? Epidemiologie ? Nukleare Sicherheit ? Beschäftigungsstruktur ? Krankheit ? Tabakrauchen ? Risiko ?
Region: Peine
Bounding boxes: 10.2352° .. 10.2352° x 52.31928° .. 52.31928°
License: other-closed
Language: Deutsch
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