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Amtlicher Anzeiger, Teil II des Hamburgischen Gesetz- und Verordnungsblattes

Nach hamburgischem Landesrecht werden Veröffentlichungen durch Abdruck im Hamburgischen Gesetz- und Verordnungsblatt vorgenommen. Rechtsverbindlich ist deshalb ausschließlich die gedruckte Ausgabe des Hamburgischen Gesetz- und Verordnungsblattes Teile I und II (Amtlicher Anzeiger). Eine Inhaltssuche kann nur über die Internetseite der <a href="http://www.luewu.de/anzeiger/">Firma Lütcke & Wulff</a> erfolgen.

4G-PHOTOCAT - Fourth generation photocatalysts: nano-engineered composites for water decontamination in low-cost paintable photoreactors

The project 4G-PHOTOCAT allies the expertise of 7 academic and 3 industrial partners from 5 EU countries (Germany, United Kingdom, Czech Republic, Poland, and Finland) and 2 ASEAN countries (Malaysia and Vietnam) for the development of a novel generation of low-cost nano-engineered photocatalysts for sunlight-driven water depollution. Through rational design of composites in which the solar light-absorbing semiconductors are coupled to nanostructured redox co-catalysts based on abundant elements, the recombination of photogenerated charges will be suppressed and the rate of photocatalytic reactions will be maximized. In order to achieve fabrication of optimal architectures, advanced chemical deposition techniques with a high degree of control over composition and morphology will be employed and further developed. Furthermore, novel protocols will be developed for the implementation of the photocatalysts into a liquid paint, allowing for the deposition of robust photoactive layers onto flat surfaces, without compromising the photoactivity of immobilized photocatalysts. Such paintable photoreactors are envisaged particularly as low-cost devices for detoxification of water from highly toxic persistent organic pollutants which represent a serious health issue in many remote rural areas of Vietnam and other countries. The 4G-PHOTOCAT project will provide novel scientific insights into the correlation between compositional/structural properties and photocatalytic reaction rates under sunlight irradiation, as well as improved fabrication methods and enhanced product portfolio for the industrial partners. Finally, 4G-PHOTOCAT will lead to intensified collaboration between scientists working at the cutting edge of synthetic chemistry, materials science, heterogeneous photocatalysis, theoretical modelling, and environmental analytics, as well as to unique reinforcement of cooperation between scientists and industry partners from EU and ASEAN countries.

Vectors of Change in Oceans and Seas Marine Life, Impact on Economic Sectors (VECTORS)

Marine life makes a substantial contribution to the economy and society of Europe. VECTORS will elucidate the drivers, pressures and vectors that cause change in marine life, the mechanisms by which they do so, the impacts that they have on ecosystem structures and functioning, and on the economics of associated marine sectors and society. VECTORS will particularly focus on causes and consequences of invasive alien species, outbreak forming species, and changes in fish distribution and productivity. New and existing knowledge and insight will be synthesised and integrated to project changes in marine life, ecosystems and economies under future scenarios for adaptation and mitigation in the light of new technologies, fishing strategies and policy needs. VECTORS will evaluate current forms and mechanisms of marine governance in relation to the vectors of change. Based on its findings, VECTORS will provide solutions and tools for relevant stakeholders and policymakers, to be available for use during the lifetime of the project. The project will address a complex array of interests comprising areas of concern for marine life, biodiversity, sectoral interests, regional seas, and academic disciplines as well as the interests of stakeholders. VECTORS will ensure that the links and interactions between all these areas of interest are explored, explained, modelled and communicated effectively to the relevant stakeholders. The VECTORS consortium is extremely experienced and genuinely multidisciplinary. It includes a mixture of natural scientists with knowledge of socio-economic aspects, and social scientists (environmental economists, policy and governance analysts and environmental law specialists) with interests in natural system functioning. VECTORS is therefore fully equipped to deliver the integrated interdisciplinary research required to achieve its objectives with maximal impact in the arenas of science, policy, management and society.

Development of an integrated biorefinery for processing chitin rich biowaste to specialty and fine chemicals (CHIBIO)

The current project proposal discloses a novel biorefinery process for a sustainable, waste free, low energy conversion route of negative value marine waste streams into high value, high performance chemical intermediates and products for the polymer industry. The project has a strong emphasis on technology development and transfer to low-tech and developing countries in the EU and associated ICPC and therefore will significantly contribute to the technological and economic leadership of the EU. The technologies disclosed in this project will foster the natural growth of sustainable economies in the EU and beyond by eliminating the need for fossil resources to preserve and exceed the current standard of living. The innovative technologies developed in this project will apply novel concepts for the production of bio-based platform chemicals that act as 'drop-ins' for existing and novel polymer production processes with high atom efficiencies. The unique assembly of the current consortium consisting of academics, SME's and large scale chemical industry partners, clearly has the scientific and technical expertise to rapidly transform laboratory based results into novel product lines at an accelerated time frame. As a part of the strategy the consortium has included Demonstration Activities as require by the FP7-KBBE-Call.

Improvement of forest management key strategies: a contribution to conservation and sustainable land use

In spite of a variety of efforts, tropical forests are still threatened by exploitation and conversion to agricultural land-use. Besides legal protection, sustainable management concepts are essential for stable conservation of these ecosystems. This project aims at identifying and optimizing the potentials for forest management for three different ecosystems (Dry Forest, Tropical Mountain Rain Forest, Paramo) along a height- and climate gradient in Southern Ecuador. Therefore, multiple and locally differentiated aspects of forest management have to be considered: the direct provision of goods (timber and non-timber forest products) as well as ecosystem services (carbon sequestration, water regulation), which are of increasing importance; moreover, the effects of forest management on biodiversity and the impacts of climate change on resilience indicators and the potential distribution of selected species with high potential for sustainable management or conservation should be investigated. First of all, the most important forest structure types and possible improvements of management alternatives have to be identified at the three sites for the assessment of different management concepts. The alternatives will be tested on experimental field plots and consequently monitored for their impacts on the locally most important criteria of forest management. A sound decision support tool will be developed, taking into account uncertainties with regard to input parameters and the relevance of different criteria of forest management. Therefore, Multi Criteria Decision Analysis will be used to generate locally adapted management concepts for the different ecosystems. Those concepts should be able to consider the multiple functions of forest management and will represent the forestry component in sustainable land-use models. The comprehensive studies will be carried out in close cooperation with other scientific teams from Germany and Ecuador as well as local institutions of relevance for forest management. The direct involvement of Ecuadorian students and young academics and the integration of the investigations in educational concepts will contribute to capacity building and local efforts for the enhancement of environmental competencies. Moreover, the experimental field plots will serve in parts as demonstration objects for the implementation of sustainable forest management concepts.

FP7-PEOPLE, Mechanistic effect models for the ecological risk assessment of chemicals (CREAM)

There is widespread concern about how production and use of chemicals affect the environment. Yet food production and benefits of chemical products are vital for the functioning of European societies. In order to ensure sustainable use, EU regulations require extensive risk assessment before a chemical is approved for use. Current risk assessments focus on risk at the level of individual organisms, but according to EU directives the protection goal aims at achieving sustainable populations. Population-level effects depend not only on exposure and toxicity, but also on important ecological factors that are impossible to fully address empirically. Mechanistic effect models (MEMs) enable the integration of these factors, thus increasing the ecological relevance of risk assessments as well as providing vital understanding of how chemicals interact with ecosystems. Such understanding is crucial for improving risk mitigation strategies and ecosystem management. So far, however, regulators and industry have lacked understanding of the potential benefits that MEMs can deliver, and academics have been inconsistent in the approaches applied. This has led to scepticism about models, preventing a wider use of MEMs in risk assessment. Examples clearly demonstrating the power of MEMs for risk assessment are urgently needed, and industry, academia and regulatory authorities across Europe need scientists that are trained in both MEMs and regulatory risk assessment. CREAM will develop and experimentally validate a suite of MEMs for organisms relevant for chemical risk assessments. The consortium includes the main sectors involved (industry, academia, regulators) and will formulate Good Modelling Practice that will be followed in all individual projects, thus leading to consistency and transparency. CREAM will provide world class training for the next generation of ecological modellers, emphasizing transparency and rigorous model evaluation as core elements of the modelling process.

Bioactive natural products - linking chemical and biological information for lead discovery, preliminary SAR and assessment of undesired pharmacological properties

Small molecule natural products are a prolific source of inspiration for the development of new drugs, and essential tools in basic biomedical research as probes of biological functions. The contribution of academic laboratories in natural products discovery has been essential. The limiting factor of traditional approaches in bioactivity-directed natural product research has been the tedious process of purification and identification of active molecules from a highly complex extract matrix. Recent technological advances enable substantial improvements in efficiency via a consequential miniaturization of the screening and discovery process, and automation of certain process steps. The aim of the project is to discover small molecule natural products leads from plants and fungi acting against clinically relevant and/or emerging targets in important disease areas. The targets have been selected on the basis of specific criteria, such as (i) novelty and importance of target; (ii) lack of specific/selective inhibitors; (iii) need for enhancement of structural diversity of ligands; (iv) difficulty/impossibility to use rational drug discovery approaches; (v) access to animal models. Indications include CNS (selective GABA-A receptor agonists), inflammation and cancer (modulation of angiogenesis and lymphangiogenesis, inhibition of PI3 kinases). In addition, a screening for hERG channel inhibition will be carried out as the currently most critical anti-target in drug discovery & development. An extract library and a technology platform for the miniaturized discovery of natural products will be used. The library consists of currently 1000 plant and fungal extracts. An ethnomedicine-based focussed sub-library will be specifically tested for GABAA receptor agonistic properties. All process steps in the screening and consecutive lead identification are miniaturized, in part automated, and based on the 96-well microtiter footprint. Most of the assays are via external collaborations, and some assays involving cell signalling are established in-house. Prioritized extracts are submitted to HPLC-based activity profiling with microtiter-based fractionation of column effluent, and simultaneous on-line spectroscopic (PDA, ion-trap ESI and APCI-MS, and ESI-TOF) analysis. Compound dereplication and identification is supported by off-line microprobe NMR spectroscopy. Around the active target molecules, structurally related compounds will be characterized to generate small 'virtual' libraries for preliminary structure activity relationships. Calculation of physico-chemical data and secondary bioassays will characterize leads, and shortlisted compounds will be tested in vivo for proof of concept. For this purpose, compounds of interest are isolated in a targeted manner in amounts of up to several hundred mg.

Production of activated clays for low-cost building materials in developing countries

Building Materials are a basic need, which is often difficult to meet in developing countries. Concrete is the building material best suited to meet these demands, although cement, the central ingredient is often disproportionately expensive in developing counties. The most promising option to lower costs (and environmental impact) is to blend conventional Portland cement with pozzolanic materials. The aim of this project is to develop technologies appropriate for the small scale, local production of pozzolans from clay (a material widely available) in conjunction with the exploitation of waste biomass for combined heat and power production. The modular concept of a clay activation unit, CAU to be coupled with a biomass boiler, will give the flexibility to adapt the solution to local conditions. We have already demonstrated that relatively common (low grade) clayey soils can be activated to give a pozzolan similar in performance to fly ash (from coal fired electricity production) widely used in the developed world. Results also indicate that it is possible to improve their reactivity by using and optimizing flash calcination, to allow high levels of substitution and very significant improvements in cost/performance ratio. To achieve this we need also to look at the performance of the activated clays in concrete from the point of view of rheology, hardening and durability to enable optimum cost/performance to be achieved according to local materials and applications. The partnership between LMC, EPFL and two academic groups in Cuba has already been established in a previous project. Furthermore, one of the Cuban partners plays a leading role in ECOSUR (a Swiss NGO) which has established workshops, producing low cost building materials, in many developing countries. In the first part of the project significant scientific advances were made, which enabled a huge acceleration in progress, relative to previous work by the Cuban partners alone. In addition, 3 Cuban PhD students spent several months working in the Swiss laboratory and have now returned to Cuba to continue their research. In this project, funding is requested for one PhD student to be based in Switzerland, who will work closely with 3 Cuban PhD Student (funded be the Cuban government). On the Cuban side, funds are requested for essential equipment and to fund the stays of the students at EPFL. Each of the Cuban students will spend 4-8 months working at EPFL during the course of the project.

FP6-SUSTDEV, An innovative approach of Integrated Wildland Fire Management regulating the wildfire problem by the wise use of fire: solving the FIRE PARADOX (FIRE PARADOX)

Wildfires are a major problem for many European societies threatening human lives and property with disastrous impacts particularly at the wildland-urban interface. On the other hand humans always used fire as a tool to regulate nature and traditional use of fire is known in many regions of Europe. The understanding of this paradox, is thus essential for finding solutions for integrated wildland fire management.This concept requires considering the various aspects of fire, from its use as a planned management practice (prescribed fire) to the initiation and propagation of unplanned fires (wildfires) and to the use of fire in fighting wildfires (suppression fire). Prescribed or suppression fires will therefore set the limits for wildfires by vontrolling their spatial extent, intensity and impacts. This is the main approach adopted aiming at the creation of the scientific and technological bases for new practices and policies under integrated wildland fire management and in the development of strategies for its implementation in Europe. Three major domains of related activities were considered: research, development and dissemination. In research, the project will focus on understanding the machanisms and modelling the processes associated with fire, from physics to biology and social sciences. Experimental and sampling methods will be used. The scientific and technical knowledge gathered will allow the development of a technological platform that will integrate the fire model, the temporal and spatial variability of fuels and weather, and the potential ecological and social-economical impacts. Documentation and demonstration platforms will also be extensively used for dissemination, focusing in the development of stategies for public awarness, academic and professional training using new communication technologies and networks, and for the implementation of new practices, policies and regulations under the concept of integrated wildland fire management. Prime Contractor: Universidade Tecnica de Lisboa, Instituto Superior de Agronomia; Lisboa; Portugal.

Reverse Electrodialysis Alternative Power Production (REAPOWER)

The project is focusing on the salinity gradient power reverse electro-dialysis (SGP-RE) process. It has been shown in scientific papers that the performance of the process can be increased by an order of magnitude when brine and sea or brackish water are used for the creation of the salinity gradient rather than the current approach of seawater with fresh water. The overall potential is very high and the REAPower project aims to enable the SGP-RE technology to play an important role in the energy mix of the next decades, contributing to the major objectives of energy policy for sustainability, security of supply and competitiveness. The following specific scientific and technological objectives are expected to be achieved within the life-time of the project: (i) Create materials and components tailored to the requirements of the process, including the membranes, spacers, electrodes and electrolyte. (ii) Optimise the design of the SGP-RE cell pairs and stack using a computer modelling tool developed for that purpose (iii) Verify the model, and assess the developed materials, components and design through tests on laboratory stacks. (iv) Evaluate and improve the performance of the overall system through tests on a prototype fed with real brine from a salt pond (v) Evaluate the results, analyse the economics, assess the environmental impacts and define the next necessary R&D activities for further development of the technology. The REAPower project explores a new path that has been so far only theoretically analysed. A highly innovative novel technology will be applied that overcomes the limitations of the current approach. The multidisciplinary consortium brings together key players from the industry and the academic world to work across traditional boundaries. The development of the new materials and components will contribute to the establishment of a strong scientific and technical base for European science and technology in this emerging area of energy research.

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