Nach hamburgischem Landesrecht werden Veröffentlichungen durch Abdruck im Hamburgischen Gesetz- und Verordnungsblatt vorgenommen. Rechtsverbindlich ist deshalb ausschließlich die gedruckte Ausgabe des Hamburgischen Gesetz- und Verordnungsblattes Teile I und II (Amtlicher Anzeiger). Eine Inhaltssuche kann nur über die Internetseite der <a href="http://www.luewu.de/anzeiger/">Firma Lütcke & Wulff</a> erfolgen.
ROBUST DSC aims to develop materials and manufacturing procedures for Dye Sensitized Solar Cells (DSC) with long lifetime and increased module efficiencies (7Prozent target). The project intends to accelerate the exploitation of the DSC technology in the energy supply market. The approach focuses on the development of large area, robust, 7Prozent efficient DSC modules using scalable, reproducible and commercially viable fabrication procedures. In parallel with this objective, more fundamental research, employing new materials and device configurations, will target increasing the efficiency of labscale DSC to 14Prozent. Progress on labscale devices will be fed directly into module development. The approach is based on the use of innovative low-cost materials, scalable manufacturing techniques, predictive device models and in-and outdoor lifetime testing. A sound and scientific understanding of the basic procedures to manufacture the cells and a thorough knowledge of the fundamental processes in the cell are important tools for our success. The partnership consists of: two SMEs (Orionsolar and G24i) that are committed to large-scale production of DSC, one industry (Corning) that has proven experience on inorganic frits for sealing of a variety of applications, three research institutes (ECN, IVF, FISE) with expertise in the field of long-term testing, up-scaling and module fabrication and four academic partners, world leaders in both new materials and concepts, and in fundamental research on cell function and modelling (EPFL, IMPERIAL, ICIQ, UAM). We anticipate that this project will result in the demonstration of a new scalable, low cost, photovoltaic technology. It will therefore form the basis of a potentially substantial business opportunity aiming at developing a new solar cell product with cost and payback characteristics strongly advantaged over existing technologies.
Natural products remain an important source for drugs and a source of inspiration for medicinal chemists for the design of synthetic drugs and probes for the study of biological functions. The contribution of academic laboratories in natural products discovery has been substantial. The limiting factor of pharmaceutical natural product research has been with the tedious process of purification and identification of the lead molecules from the highly complex crude extract. Recent technological advances enable now a miniaturization of the screening and discovery process for natural product leads. The proposal here is for the purchase of a 500 MHz NMR spectrometer specifically equipped for the measurement of mass limited samples. It includes a recently commercialized 1 mm probe and autosampler and is capable of recording 1D and 2D NMR spectra with microgram (20-100 myg) amounts of natural products and synthetic drug-like molecules. The spectrometer is configured to fit into the technology platforms and the workflows of the Drug Screening Group of the Swiss Tropical Institute and the Institute of Pharmaceutical Biology. The instrument shall be used for various interdisciplinary projects of the two principal applicants and for a consortium which is being established. The major use will be for HPLC-based lead discovery in the area of Alzheimer's disease, Malaria, and neglected tropical diseases. The instrument will also be employed for metabolic fingerprinting of selected plants and phytomedicines. A third application will be in the analysis of compound libraries from external sources which are screened by the applicants in the context of the principal projects. An NMR instrument with this configuration is currently not in operation at a Swiss university. It is the missing link in a technology platform established at the laboratories of the two applicants. This platform should enable a paradigm shift in the way how natural product leads are identified, namely by miniaturizing the entire process of screening, separation and lead identification to the microgram level. A significant gain in efficiency of the discovery process and, thus, in research productivity, both qualitative and quantitative, is anticipated. The equipment will also be of interest to all those scientists in the biomedical sciences who need structural information from mass limited samples such as, for example drug metabolites.
A reliable assessment of future climate impacts in Austria makes necessary to provide regional climate model (RCM) runs, and additional tasks to deliver high resolution downscaled datasets for past and future climate targeting the entire eastern alps covering Austria. The project reclip:more (Research for Climate Protection: Model Run Evaluation) is a cooperation of five academic institutions. The major scientific goals are: quantify the uncertainties of regional climate simulations elated to observed climate data, investigate the sensitivity of regional climate simulations and interpolated climate data to the influence of different model parameters and data processing techniques, deliver regional climate change scenarios at mesoscale and microscale resolutions for the eastern Alps covering Austria . To achieve this, data preparations, a set of common model experiments and data evaluations have to be carried out with sensitivity studies. In project year 1 (Nov. 2003 to June 2004, postponed to Oktober 2004) the reclip:more-teams focused on preparative work for the 10-year simulations, using ERA-40 data and ECHAM5 control runs of current climate from the 1990ies. Furthermore a huge number of sensitivity studies aiming at finding the optimal RCM-setup (e.g. extent and position of the nests, nesting strategy, parameterization, etc.) were made. Additionally, different examinations concerning further statistical downscaling and on the preparation of validation data and methods were done. To compare the model results with observation data, monitoring data sets for Austria and synoptic data sets for entire Europe have been prepared. In the 2nd year (Nov. 2004 to June to Oktober 2005) the emphasis lay on the retrospective model runs with the two RCMs and the re-analysis/GCM-datasets for 1981-1990. Also a number of short episode runs and 7 annual runs with different settings were evaluated. At the end a comprehensive benchmarking of the model-outputs was done. At the same time the prospective model runs were prepared. The second main topic was the development of downscaling techniques for the regionalization of observation data and model results in the Alpine region. Downscaling of model results for a resolution of 1 km have been derived for temperature, precipitation and solar radiation with terrain-related response variables (for irradiation additionally with radiation-physics-related numerical functions). For near-surface-wind a method was accomplished by dynamical downscaling via MM5 and CALMET. In year 3 the prospective model runs for 2041-2050 will follow. With the in PJ2 developed techniques the model results will be downscaled to 1km for three study regions in Austria . At the end the transient high resolution results and monitoring data will be provided to the interested climate community.
Transmembrane ion channels regulate the movement of ions (particularly Na+, K+, Ca2+ and Cl-) across cellular membranes, and are critical to numerous aspects of neurobiology. Cells express a diverse array of ion-channel proteins that vary widely in their ion selectivity and in their modulation by ligands (such as neurotransmitters) or by membrane voltage. Potassium is the most abundant cellular cation and the imbalance of potassium across the cell membrane is responsible for the maintenance of the membrane potential. Activation of different K+ selective ion channels is essential to control the excitability of nerve and muscle cells. Considerable interest has been focused on the roles of potassium channels in shaping the physiological behaviours of both excitable and non-excitable cells. Pharmacological tools, such as inhibitors have been used to characterize individual classes of channels but for many potassium channels specific blockers are not available. Heterologous expression of ion channel proteins in yeast provides an alternative to animal testing for functional (pharmacological) analysis as well as providing a robust, cell-based system for rapid identification of new lead compounds. K+-channel modulators are valuable pharmacological tools with therapeutic potential.The cloning and characterization of the yeast K+ transport system, and most recently, of the outward rectifying K+channel enabled the generation of yeast mutants lacking those transporters and channels. This advance has made possible new approaches for the analysis of mammalian K+ selective channels by functional complementation of yeast mutants. The development of a yeast-based expression and screening system will play a key role in the development of in-vitro pharmacological tests for chemical and pharmacological agents.The development of a yeast screening systems provides useful tools both for academic and industrial applications in an EC wide strategy.
The project 4G-PHOTOCAT allies the expertise of 7 academic and 3 industrial partners from 5 EU countries (Germany, United Kingdom, Czech Republic, Poland, and Finland) and 2 ASEAN countries (Malaysia and Vietnam) for the development of a novel generation of low-cost nano-engineered photocatalysts for sunlight-driven water depollution. Through rational design of composites in which the solar light-absorbing semiconductors are coupled to nanostructured redox co-catalysts based on abundant elements, the recombination of photogenerated charges will be suppressed and the rate of photocatalytic reactions will be maximized. In order to achieve fabrication of optimal architectures, advanced chemical deposition techniques with a high degree of control over composition and morphology will be employed and further developed. Furthermore, novel protocols will be developed for the implementation of the photocatalysts into a liquid paint, allowing for the deposition of robust photoactive layers onto flat surfaces, without compromising the photoactivity of immobilized photocatalysts. Such paintable photoreactors are envisaged particularly as low-cost devices for detoxification of water from highly toxic persistent organic pollutants which represent a serious health issue in many remote rural areas of Vietnam and other countries. The 4G-PHOTOCAT project will provide novel scientific insights into the correlation between compositional/structural properties and photocatalytic reaction rates under sunlight irradiation, as well as improved fabrication methods and enhanced product portfolio for the industrial partners. Finally, 4G-PHOTOCAT will lead to intensified collaboration between scientists working at the cutting edge of synthetic chemistry, materials science, heterogeneous photocatalysis, theoretical modelling, and environmental analytics, as well as to unique reinforcement of cooperation between scientists and industry partners from EU and ASEAN countries.
Marine life makes a substantial contribution to the economy and society of Europe. VECTORS will elucidate the drivers, pressures and vectors that cause change in marine life, the mechanisms by which they do so, the impacts that they have on ecosystem structures and functioning, and on the economics of associated marine sectors and society. VECTORS will particularly focus on causes and consequences of invasive alien species, outbreak forming species, and changes in fish distribution and productivity. New and existing knowledge and insight will be synthesised and integrated to project changes in marine life, ecosystems and economies under future scenarios for adaptation and mitigation in the light of new technologies, fishing strategies and policy needs. VECTORS will evaluate current forms and mechanisms of marine governance in relation to the vectors of change. Based on its findings, VECTORS will provide solutions and tools for relevant stakeholders and policymakers, to be available for use during the lifetime of the project. The project will address a complex array of interests comprising areas of concern for marine life, biodiversity, sectoral interests, regional seas, and academic disciplines as well as the interests of stakeholders. VECTORS will ensure that the links and interactions between all these areas of interest are explored, explained, modelled and communicated effectively to the relevant stakeholders. The VECTORS consortium is extremely experienced and genuinely multidisciplinary. It includes a mixture of natural scientists with knowledge of socio-economic aspects, and social scientists (environmental economists, policy and governance analysts and environmental law specialists) with interests in natural system functioning. VECTORS is therefore fully equipped to deliver the integrated interdisciplinary research required to achieve its objectives with maximal impact in the arenas of science, policy, management and society.
The current project proposal discloses a novel biorefinery process for a sustainable, waste free, low energy conversion route of negative value marine waste streams into high value, high performance chemical intermediates and products for the polymer industry. The project has a strong emphasis on technology development and transfer to low-tech and developing countries in the EU and associated ICPC and therefore will significantly contribute to the technological and economic leadership of the EU. The technologies disclosed in this project will foster the natural growth of sustainable economies in the EU and beyond by eliminating the need for fossil resources to preserve and exceed the current standard of living. The innovative technologies developed in this project will apply novel concepts for the production of bio-based platform chemicals that act as 'drop-ins' for existing and novel polymer production processes with high atom efficiencies. The unique assembly of the current consortium consisting of academics, SME's and large scale chemical industry partners, clearly has the scientific and technical expertise to rapidly transform laboratory based results into novel product lines at an accelerated time frame. As a part of the strategy the consortium has included Demonstration Activities as require by the FP7-KBBE-Call.
The project is focusing on the salinity gradient power reverse electro-dialysis (SGP-RE) process. It has been shown in scientific papers that the performance of the process can be increased by an order of magnitude when brine and sea or brackish water are used for the creation of the salinity gradient rather than the current approach of seawater with fresh water. The overall potential is very high and the REAPower project aims to enable the SGP-RE technology to play an important role in the energy mix of the next decades, contributing to the major objectives of energy policy for sustainability, security of supply and competitiveness. The following specific scientific and technological objectives are expected to be achieved within the life-time of the project: (i) Create materials and components tailored to the requirements of the process, including the membranes, spacers, electrodes and electrolyte. (ii) Optimise the design of the SGP-RE cell pairs and stack using a computer modelling tool developed for that purpose (iii) Verify the model, and assess the developed materials, components and design through tests on laboratory stacks. (iv) Evaluate and improve the performance of the overall system through tests on a prototype fed with real brine from a salt pond (v) Evaluate the results, analyse the economics, assess the environmental impacts and define the next necessary R&D activities for further development of the technology. The REAPower project explores a new path that has been so far only theoretically analysed. A highly innovative novel technology will be applied that overcomes the limitations of the current approach. The multidisciplinary consortium brings together key players from the industry and the academic world to work across traditional boundaries. The development of the new materials and components will contribute to the establishment of a strong scientific and technical base for European science and technology in this emerging area of energy research.
Objective: The primary aim of the SIINN ERA-NET is to promote the rapid transfer of the results of nano-science and nanotechnology (N&N) research into industrial application by helping to create reliable conditions. In order to strengthen the European Research Area and to coordinate N&N-related R&D work, the project has the aim of bringing together a broad network of ministries, funding agencies, academic and industrial institutions to create a sustainable transnational programme of joint R&D in N&N. The commercial application of nano-materials (NMs) products is increasing rapidly, but one important question, the safety of NMs, still represents a barrier to their wide innovative use. Therefore the first priority of SIINN is to focus on developing a consolidated framework to address nano-related risks and the management of these risks for humans and the environment by investigating the toxicological behaviour of NMs. European R&D activities in N&N remain largely uncoordinated and fragmented, resulting in the sub-optimal use of available resources, such as human resources, research equipment and funding. Since available data on their toxicological behaviour is often scant, unreliable or contradictory, the SIINN Project will focus on ways of remedying this situation. After defining the criteria important for NM toxicology, the environmental health and safety (EHS) information currently available to Europe will be examined. Liaisons will strategically be established and maintained. They will network with organisations looking into the EHS of NMs within Europe and abroad with the aim of continually exchanging information with these. Available information will be examined for their reliability in respect of the assessment of the risks of NMs towards human health and to the environment and major knowledge gaps identified. At least two joint, transnational calls will be organised during the initial lifetime of SIINN in order to fill these gaps.
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