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Objective: The primary aim of the SIINN ERA-NET is to promote the rapid transfer of the results of nano-science and nanotechnology (N&N) research into industrial application by helping to create reliable conditions. In order to strengthen the European Research Area and to coordinate N&N-related R&D work, the project has the aim of bringing together a broad network of ministries, funding agencies, academic and industrial institutions to create a sustainable transnational programme of joint R&D in N&N. The commercial application of nano-materials (NMs) products is increasing rapidly, but one important question, the safety of NMs, still represents a barrier to their wide innovative use. Therefore the first priority of SIINN is to focus on developing a consolidated framework to address nano-related risks and the management of these risks for humans and the environment by investigating the toxicological behaviour of NMs. European R&D activities in N&N remain largely uncoordinated and fragmented, resulting in the sub-optimal use of available resources, such as human resources, research equipment and funding. Since available data on their toxicological behaviour is often scant, unreliable or contradictory, the SIINN Project will focus on ways of remedying this situation. After defining the criteria important for NM toxicology, the environmental health and safety (EHS) information currently available to Europe will be examined. Liaisons will strategically be established and maintained. They will network with organisations looking into the EHS of NMs within Europe and abroad with the aim of continually exchanging information with these. Available information will be examined for their reliability in respect of the assessment of the risks of NMs towards human health and to the environment and major knowledge gaps identified. At least two joint, transnational calls will be organised during the initial lifetime of SIINN in order to fill these gaps.
There is enormous economic potential for the application of embedded optimization technologies in embedded systems design. Recent advances in the performance of embedded hardware platforms, in combination with fundamental improvements in optimization theory and algorithms, have opened the door to widespread applications over the next decade. Embedded optimization will enable huge energy and resource savings, increased safety, and improved fault detection across a wide a range of industrial applications in the mechatronic, automotive, process control and aerospace sectors. In order to realize the full potential of optimization in embedded systems, their design must also be supported by a focussed set of tools enabling the rapid transfer of novel high-performance algorithms to practical applications. The EMBOCON consortium will enable widespread application of real-time optimization in embedded systems through: - Tailoring of customized numerical algorithms to increase their robustness and efficiency on embedded systems - Enabling real-time optimization on cheap industry-standard hardware platforms - Defining a common user interface for optimization technologies to facilitate technology transfer to industry - Performing challenging case studies in cooperation with industrial partners to demonstrate technological maturity. The EMBOCON consortium will strengthen a network of world-leading academic and industrial partners with complementary expertise in control, optimization and embedded systems in a range of industrial applications. Particular emphasis is placed on close collaboration between mathematical algorithm developers, control theorists, hardware specialists and industrial application engineers. The network will consolidate and extend Europe's position as the world research leader in these areas and foster strong collaborative links between European academia and industry. Prime Contractor: University London, Imperial College of Science, Technology and Medicine, Faculty of Engineering, Level 2 Faculty; London; United Kingdom.
Building Materials are a basic need, which is often difficult to meet in developing countries. Concrete is the building material best suited to meet these demands, although cement, the central ingredient is often disproportionately expensive in developing counties. The most promising option to lower costs (and environmental impact) is to blend conventional Portland cement with pozzolanic materials. The aim of this project is to develop technologies appropriate for the small scale, local production of pozzolans from clay (a material widely available) in conjunction with the exploitation of waste biomass for combined heat and power production. The modular concept of a clay activation unit, CAU to be coupled with a biomass boiler, will give the flexibility to adapt the solution to local conditions. We have already demonstrated that relatively common (low grade) clayey soils can be activated to give a pozzolan similar in performance to fly ash (from coal fired electricity production) widely used in the developed world. Results also indicate that it is possible to improve their reactivity by using and optimizing flash calcination, to allow high levels of substitution and very significant improvements in cost/performance ratio. To achieve this we need also to look at the performance of the activated clays in concrete from the point of view of rheology, hardening and durability to enable optimum cost/performance to be achieved according to local materials and applications. The partnership between LMC, EPFL and two academic groups in Cuba has already been established in a previous project. Furthermore, one of the Cuban partners plays a leading role in ECOSUR (a Swiss NGO) which has established workshops, producing low cost building materials, in many developing countries. In the first part of the project significant scientific advances were made, which enabled a huge acceleration in progress, relative to previous work by the Cuban partners alone. In addition, 3 Cuban PhD students spent several months working in the Swiss laboratory and have now returned to Cuba to continue their research. In this project, funding is requested for one PhD student to be based in Switzerland, who will work closely with 3 Cuban PhD Student (funded be the Cuban government). On the Cuban side, funds are requested for essential equipment and to fund the stays of the students at EPFL. Each of the Cuban students will spend 4-8 months working at EPFL during the course of the project.
Objective: The proposed project is designed to address the problem of pollution of the environment by road vehicles as denned under the Thematic Priority 1.6.2, Sustainable Surface Transport relating to the Work Programme 'Integrating and strengthening the European Research Area'. The research activities of the consortium will be based around state of the art developments in the area of optical fibre sensor and intelligent instrumentation technology to formulate a system for on line monitoring of exhaust emissions from road vehicles. The application of this technology to resolving the problems of atmospheric pollutants and their regional impacts is therefore highly appropriate to the issue identified in the thematic roadmap i.e. 'New technologies and concepts for all surface transport modes'. The consortium which will execute the research programme comprises six members from four EC member states. They include four academic institutions, an SME and an end user (a major European car manufacturer). Their combined expertise and knowledge of the technological and business issues will facilitate the rapid development of the technology into a demonstratable prototype within the three year lifetime of the project. The project's technical objectives are summarised as follows: -. To set up laboratory based test facilities such that the sensor systems may be characterised in a precisely controlled and reproducible manner. Therefore, individual parameters such as optical absorption and scattering may be studied in isolation as well as collectively.. To isolate and identify the optical signals arising from contaminants present in the complex mixtures of exhaust systems of a wide range of vehicles using advanced and novel optical fibre based spectroscopie interrogation techniques. To develop novel optical fibre sensors which are miniature and robust in their construction and may be fitted...
Transmembrane ion channels regulate the movement of ions (particularly Na+, K+, Ca2+ and Cl-) across cellular membranes, and are critical to numerous aspects of neurobiology. Cells express a diverse array of ion-channel proteins that vary widely in their ion selectivity and in their modulation by ligands (such as neurotransmitters) or by membrane voltage. Potassium is the most abundant cellular cation and the imbalance of potassium across the cell membrane is responsible for the maintenance of the membrane potential. Activation of different K+ selective ion channels is essential to control the excitability of nerve and muscle cells. Considerable interest has been focused on the roles of potassium channels in shaping the physiological behaviours of both excitable and non-excitable cells. Pharmacological tools, such as inhibitors have been used to characterize individual classes of channels but for many potassium channels specific blockers are not available. Heterologous expression of ion channel proteins in yeast provides an alternative to animal testing for functional (pharmacological) analysis as well as providing a robust, cell-based system for rapid identification of new lead compounds. K+-channel modulators are valuable pharmacological tools with therapeutic potential.The cloning and characterization of the yeast K+ transport system, and most recently, of the outward rectifying K+channel enabled the generation of yeast mutants lacking those transporters and channels. This advance has made possible new approaches for the analysis of mammalian K+ selective channels by functional complementation of yeast mutants. The development of a yeast-based expression and screening system will play a key role in the development of in-vitro pharmacological tests for chemical and pharmacological agents.The development of a yeast screening systems provides useful tools both for academic and industrial applications in an EC wide strategy.
The project 4G-PHOTOCAT allies the expertise of 7 academic and 3 industrial partners from 5 EU countries (Germany, United Kingdom, Czech Republic, Poland, and Finland) and 2 ASEAN countries (Malaysia and Vietnam) for the development of a novel generation of low-cost nano-engineered photocatalysts for sunlight-driven water depollution. Through rational design of composites in which the solar light-absorbing semiconductors are coupled to nanostructured redox co-catalysts based on abundant elements, the recombination of photogenerated charges will be suppressed and the rate of photocatalytic reactions will be maximized. In order to achieve fabrication of optimal architectures, advanced chemical deposition techniques with a high degree of control over composition and morphology will be employed and further developed. Furthermore, novel protocols will be developed for the implementation of the photocatalysts into a liquid paint, allowing for the deposition of robust photoactive layers onto flat surfaces, without compromising the photoactivity of immobilized photocatalysts. Such paintable photoreactors are envisaged particularly as low-cost devices for detoxification of water from highly toxic persistent organic pollutants which represent a serious health issue in many remote rural areas of Vietnam and other countries. The 4G-PHOTOCAT project will provide novel scientific insights into the correlation between compositional/structural properties and photocatalytic reaction rates under sunlight irradiation, as well as improved fabrication methods and enhanced product portfolio for the industrial partners. Finally, 4G-PHOTOCAT will lead to intensified collaboration between scientists working at the cutting edge of synthetic chemistry, materials science, heterogeneous photocatalysis, theoretical modelling, and environmental analytics, as well as to unique reinforcement of cooperation between scientists and industry partners from EU and ASEAN countries.
The current project proposal discloses a novel biorefinery process for a sustainable, waste free, low energy conversion route of negative value marine waste streams into high value, high performance chemical intermediates and products for the polymer industry. The project has a strong emphasis on technology development and transfer to low-tech and developing countries in the EU and associated ICPC and therefore will significantly contribute to the technological and economic leadership of the EU. The technologies disclosed in this project will foster the natural growth of sustainable economies in the EU and beyond by eliminating the need for fossil resources to preserve and exceed the current standard of living. The innovative technologies developed in this project will apply novel concepts for the production of bio-based platform chemicals that act as 'drop-ins' for existing and novel polymer production processes with high atom efficiencies. The unique assembly of the current consortium consisting of academics, SME's and large scale chemical industry partners, clearly has the scientific and technical expertise to rapidly transform laboratory based results into novel product lines at an accelerated time frame. As a part of the strategy the consortium has included Demonstration Activities as require by the FP7-KBBE-Call.
Marine life makes a substantial contribution to the economy and society of Europe. VECTORS will elucidate the drivers, pressures and vectors that cause change in marine life, the mechanisms by which they do so, the impacts that they have on ecosystem structures and functioning, and on the economics of associated marine sectors and society. VECTORS will particularly focus on causes and consequences of invasive alien species, outbreak forming species, and changes in fish distribution and productivity. New and existing knowledge and insight will be synthesised and integrated to project changes in marine life, ecosystems and economies under future scenarios for adaptation and mitigation in the light of new technologies, fishing strategies and policy needs. VECTORS will evaluate current forms and mechanisms of marine governance in relation to the vectors of change. Based on its findings, VECTORS will provide solutions and tools for relevant stakeholders and policymakers, to be available for use during the lifetime of the project. The project will address a complex array of interests comprising areas of concern for marine life, biodiversity, sectoral interests, regional seas, and academic disciplines as well as the interests of stakeholders. VECTORS will ensure that the links and interactions between all these areas of interest are explored, explained, modelled and communicated effectively to the relevant stakeholders. The VECTORS consortium is extremely experienced and genuinely multidisciplinary. It includes a mixture of natural scientists with knowledge of socio-economic aspects, and social scientists (environmental economists, policy and governance analysts and environmental law specialists) with interests in natural system functioning. VECTORS is therefore fully equipped to deliver the integrated interdisciplinary research required to achieve its objectives with maximal impact in the arenas of science, policy, management and society.
The project is focusing on the salinity gradient power reverse electro-dialysis (SGP-RE) process. It has been shown in scientific papers that the performance of the process can be increased by an order of magnitude when brine and sea or brackish water are used for the creation of the salinity gradient rather than the current approach of seawater with fresh water. The overall potential is very high and the REAPower project aims to enable the SGP-RE technology to play an important role in the energy mix of the next decades, contributing to the major objectives of energy policy for sustainability, security of supply and competitiveness. The following specific scientific and technological objectives are expected to be achieved within the life-time of the project: (i) Create materials and components tailored to the requirements of the process, including the membranes, spacers, electrodes and electrolyte. (ii) Optimise the design of the SGP-RE cell pairs and stack using a computer modelling tool developed for that purpose (iii) Verify the model, and assess the developed materials, components and design through tests on laboratory stacks. (iv) Evaluate and improve the performance of the overall system through tests on a prototype fed with real brine from a salt pond (v) Evaluate the results, analyse the economics, assess the environmental impacts and define the next necessary R&D activities for further development of the technology. The REAPower project explores a new path that has been so far only theoretically analysed. A highly innovative novel technology will be applied that overcomes the limitations of the current approach. The multidisciplinary consortium brings together key players from the industry and the academic world to work across traditional boundaries. The development of the new materials and components will contribute to the establishment of a strong scientific and technical base for European science and technology in this emerging area of energy research.
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