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MariaBox will develop a wireless marine environment analysis device for monitoring chemical and biological pollutants while installed into a buoy, a maritime means of transport or a mooring. The device, based on novel biosensors, will be of high-sensitivity, portable and capable of repeating measurements over a long time, allowing permanent deployment at sea. The word 'MARIA' is the plural of the Latin 'mar' (sea) and expresses the wide applicability that this system offers in multiple locations where low-cost and real-time in situ analytical monitoring devices are required. The approach includes: a) a sensing and analysis box, b) a modular communication system, c) a flexible power system, d) a software platform, and e) a cell phone application. The box will transmit the collected data in real time through different channels according to local needs and geographical location: radio, GSM/GPRS/3G, WiFi, WiMAX or satellite link. The unit will be designed to be remotely controlled and will implement the OTA programming and OTA configuration features which will allow the user to update the firmware of the MariaBox unit and modify various configuration parameters wirelessly. Remote updates are a key factor in deployment scalability since it offers the only possibility of easily updating or reprogramming the devices after the initial deployment. Therefore, the maintenance costs are significantly reduced. Biosensors will be developed for 5 man-made chemicals and for 4 categories of microalgae toxins relevant to shell fish and fish farming. The novel biosensors will contribute to new standards for environmental analysis. The analytes selected for the biosensors are in line with 1) the Article 16 of the Water Framework Directive (2000/60/EC), 2) the Decision 2455/2001/EC and 3) The Commission Directive 2009/90/EC. The system developed will be demonstrated and validated in four different scenarios in selected locations in Norway, Spain, Cyprus and Ireland.
Das Projekt zielt darauf ab die genetischen Ressourcen von Leguminosen in Europa zu untersuchen um Ihre nachhaltige Produktion und Nutzung zu fördern. Neue Sorten und neue Lebens-und Futtermittel sollen die Proteinproduktion in der EU wettbewerbsfähiger und nachhaltiger machen. Kurzfristige Ziele S & T: 1. Bewertung lokaler genetischer Ressourcen von Erbse (Pisum sativum L.), Ackerbohne (Vicia faba L.) und Augenbohne (Vigna unguiculata (L.) Walp) für die Entwicklung von neuen Sorten für Lebens- und Futtermittel und die weitere Verwendung in der Zucht; 2. Entwicklung neuer Lebens- und Futtermittel aus verfügbaren europäischen Sorten von Erbse, Ackerbohne und Augenbohne; 3. Auswahl geeigneter Rhizobienstämme und arbuskulären Mykorrhizapilze zur Unterstützung der Stickstofffixierung und Entwicklung von neuen, kommerziellen Sporen-Impfstoffen; 4. Bewertung des Einflusses von Leguminosen auf die Bodeneigenschaften in nachhaltigen, regional-spezifischen Anbausystemen. Projektschwerpunkt an der BOKU sind die Wurzelsysteme.
OPTIBIOCAT is a 48 months project aimed at developing biocatalysts based on feruloyl esterases (FAEs) and glucuronoyl esterases (GEs) for production of phenolic fatty- and sugar- esters with antioxidant activity for cosmetic industry, expanding the number/type of industrial biotransformations. Selected FAEs and GEs available within the consortium will be improved for their thermo- and solvent- resistance and substrate specificity by site-directed mutagenesis and directed evolution. Novel enzymes will be discovered by mining for new genes from available genomes. An inventory of novel FAEs and GEs will be developed including 50 fungal and 500 bacterial esterases, 25 site-directed and 20 directed evolved mutants. Enzymatic performances will be optimized to enhance the yield (up to the theoretical yield of 100%) and productivity (up to 0.5-1 g/l/h) of reactions giving the main targeted antioxidants: butyl ferulate, p-coumarate, caffeate, sinapate and 5-O-(trans-feruloyl)-arabinofuranose (using FAEs), glucuronate and benzyl glucuronate (using GEs). FAEs and GEs will be also tested for production of other compounds with improved biological activity and properties of hydrophilicity/hydrophobicity for cosmetic applications. Cost-effective methods will be developed for production of the new biocatalysts, in the g/L scale, and for their technical application to produce antioxidants for cosmetic industry, up to 20L. Enzyme immobilization will increase their recyclability up to ten cycles. The ability of the developed catalysts to work in conditions miming the industrial ones with reduced use of solvents and lower temperature than the chemical routes will be demonstrated. The techno-economic viability and environmental friendliness will be assessed considering a full industrial scale scenario. OPTIBIOCAT involves a highly skilled and multidisciplinary partnership of 16 partners from 8 EU countries, and it is a strongly industry driven project through the participation of 8 SMEs and 1 large company.
Food processing activities produce in Europe large amounts of by-products and waste. Such waste streams are only partially valorized at different value-added levels (spread on land, animal feed, composting), whereas the main volumes are managed as waste of environmental concern, with relevant negative effects on the overall sustainability of the food processing industry. The main focus of NOSHAN is to investigate the process and technologies needed to use food waste for feed production at low cost, low energy consumption and with maximal valorisation of starting wastes materials. Nutritional value and functionality according to animal needs as well as safety and quality issues will be investigated and address as main leading factors for the feed production using food derived (fruit/plant and dairy). According to this not only wastes will be characterized for their nutritional potential, but suitable technologies to stabilize them and convert them into suitable raw materials for bulk feed will be researched. Two different groups of activities will be thus addressed: From one side, replacement of bulk feed ingredients (constituting up to 90-95% of feed weight) will be studied from the starting waste materials. These bulk materials could cope part of the huge amounts of food waste generated in Europe. From the other side, the valorisation of active ingredients as well as the upgrade of waste into more valuable feed additives will be studied. The later constitute approximately the half of the feed cost. The main expected result of NOSHAN project is the creation of a broad portfolio of valorised wastes for feed production. In this sense, a selection of wastes according to their potential nutritional properties, quantities produced, seasonality, possibility of stabilisation, safety and regulatory issues, cost and logistics will be performed during the first phase of the project.. In order to improve nutritional content of feed and be able to fulfil animal needs, waste will be treated alone or mixed with other waste looking for complementation and synergistic effects. The characterisation at molecular level of the different waste streams will allow providing the best technology for the best raw material to obtain the desired nutritional/functional properties. In NOSHAN a variety of high-advanced technologies for conditioning, stabilising by physico-chemical and biological strategies, extracting high-added value compounds and feed production will be tested, developed and integrated in an innovative low-cost and low energy tailor made procedure for valorising food waste for production of safety and compound functional feed. All these initiatives will be validated in in vitro and in vivo tests to the final animal derived products intended for human consumption. Therefore a whole value chain from starting raw materials to exploitable products and technologies will be covered and monitored with a LCA with a further validation using the novel ETV platform.
GRACE pursues two key research objectives: Firstly, it aims to provide comprehensive reviews of the existing evidence on the health, environmental and socio-economic impacts of GM plants - considering both risks and possible benefits. GRACEs review strategy will go beyond what has been done before. Reviews will be conducted in a systematic, transparent and inclusive way based on procedures originally developed for evidence-based medicine (systematic reviews). The results will be made accessible to the public via an open access database and other channels. Secondly, GRACE will test various types of animal feeding trials and alternative methods without the use of animals in order to determine how suitable they are and what useful scientific information they provide for health risk assessments of GM food and feed. At present there are different views at the EU level and between Member States on the need for and scientific value of such studies. The project will also check whether extended feeding trials can improve risk assessments compared to in-vitro, in-silico and omics methods available today. Transparency and user and stakeholder involvement and scrutiny are key features of GRACE. The project will be working closely with representatives from a broad range of stakeholder organisations as well as with professional risk assessors and risk managers. This includes planning and preparing the research activities as well as discussing the results and drawing conclusions. For this purpose, the GRACE project will organise workshops and conduct interviews and surveys and prepare feed-back reports to ensure that the information and the views of stakeholders can feed into this project. IFZ is leading the work package for user and stakeholder involvement and will also work on the core review process.
The objective of the PreSto GMO ERA-Net project is to map out the steps needed to create and successfully implement an ERA-Net that will coordinate transnational research on human and animal health, environmental, techno-economic, and socio-economic impacts of genetically modified organisms (GMOs). The focus will be on GMOs intentionally released into the environment and/or used immediately in feed and food applications. PreSto GMO ERA-Net brings together ministries, agencies, and funding bodies from different Members States and the scientific community to jointly prepare a strategic plan and roadmap for the implementation of the ERA-Net. In addition, the ERA-Net will explicitly take into account the wider views of a diversity of stakeholders and end-users (e. g. industry, farming organisations, civil society organisations, EU and national competent authorities, funding organisations, academia). This is intended to strengthen ownership of the ERA-Net among stakeholders in order to encourage participation of different scientific communities in the future joint transnational calls, to enhance collaboration between actors and to increase the accountability of research trajectories and outcomes. The results of the project will form the basis for a robust ERA-Net proposal. In achieving this the project work will promote the accessibility of existing scientific information to interested stakeholders and end-users, lead to the harmonisation of research requirements and capacity building within Europe, complement international developments, contribute to a more efficient use of research funds internationally and identify how strategic collaboration can be used to respond to these future research and training needs through enhancement of durable partnerships. The Graz unit of Alpen-Adria-Universität Klagenfurt is involved in two workpackages. It will lead a workpackage on stakeholder engagement and engage in another workpackage which will develop an implementation plan.
The current project proposal discloses a novel biorefinery process for a sustainable, waste free, low energy conversion route of negative value marine waste streams into high value, high performance chemical intermediates and products for the polymer industry. The project has a strong emphasis on technology development and transfer to low-tech and developing countries in the EU and associated ICPC and therefore will significantly contribute to the technological and economic leadership of the EU. The technologies disclosed in this project will foster the natural growth of sustainable economies in the EU and beyond by eliminating the need for fossil resources to preserve and exceed the current standard of living. The innovative technologies developed in this project will apply novel concepts for the production of bio-based platform chemicals that act as 'drop-ins' for existing and novel polymer production processes with high atom efficiencies. The unique assembly of the current consortium consisting of academics, SME's and large scale chemical industry partners, clearly has the scientific and technical expertise to rapidly transform laboratory based results into novel product lines at an accelerated time frame. As a part of the strategy the consortium has included Demonstration Activities as require by the FP7-KBBE-Call.
Die nachhaltige Produktion wichtiger Chemikalien, Lebensmittel- und Pharmazeutikakomponenten ist von hoher Bedeutung für die Gesellschaft und die Umwelt. Biotechnologische Produktionssysteme stellen eine sinnvolle Alternative zu den bisherigen, meist chemischen, Verfahren da. Die biotechnologische Produktionssysteme basieren jedoch bisher meist auf der Verwertung von Zuckern. Zucker, die aus Pflanzen gewonnen werden, benötigen kultivierbares Land, das mehr und mehr zur Gewinnung von Nahrungsmitteln benötigt wird. Methanol - mit einer weltweiten Produktionskapazität von mehr als 46 Millionen Tonnen pro Jahr - gilt als attraktiver alternativer Rohstoff für die biotechnologische Produktion von Spezial-, Fein- und Basischemikalien oder Kraftstoffen. Dies gilt insbesondere für den EU-Markt, wo die industrielle Biotechnologie noch durch strikte Preis- und Nutzungsregularien sowie Importlimitierungen von Agrargütern wie Mais oder Zucker behindert ist. Die Methanolversorgung kann sowohl auf fossilen, als auch auf erneuerbaren Ressourcen basieren, was es als flexiblen und nachhaltigen Rohstoff auszeichnet. In dem Projekt PROMYSE werden zum ersten Mal synthetisch-biologische Prinzipien für die Entwicklung von Zellfabriken angewendet um Methanol als generellen Rohstoff für die Produktion von Spezial- und Feinchemikalien verfügbar zu machen. Produktseitig liegt der Hauptfokus auf der Substanzklasse der Terpenoide.
The Catch-C project assesses the farm-compatibility of Best Management Practices (BMPs) that aim to promote productivity, climate change mitigation, and soil quality. These are the three overall goals of sustainable soil management. Catch-C will first (WP2) set up a typology of the main farm types and agro-ecological zones across Europe. This frame, coupled to a pan-European database of socio-economic and biophysical data, will be used for spatially organising the information collected on current management; and for up-scaling the impacts expected from changes in management. Biophysical impacts of management practices will be assessed (WP3) primarily from a large set of current field experiments, executed by the participants. BMPs will be formulated, along with their trade-offs and synergies between productivity, climate change mitigation, and soil quality. Farmers, however, often do not adopt BMPs. Identifying the barriers against adoption, and formulating ways to remove these, are core activities of the project (WP4). Catch-C will survey farmer views on BMPs in all participant countries, assess costs and benefits of implementation, identify technical and ecological bottlenecks preventing adoption, develop a decision support tool, and prioritize innovation requirements to address bottlenecks. Policy measures can promote adoption in various ways, such as voluntary measures, regulation, and economic incentives. In interaction with policy makers, Catch-C will develop (WP5) guidelines for policies that will support the adoption of BMPs; and that are consistent with regional agro-ecological and farming contexts. Dissemination (WP6) includes scientific publication; discussing project results with farmers and policy makers; making information about BMPs and their adoption available to a wider audience; and stimulating awareness about the pros and cons of BMPs for different farm types and environments in participant countries.
Objective: MAGICPAH aims to explore, understand and exploit the catalytic activities of microbial communities involved in the degradation of persistent PAHs. It will integrate (meta-) genomic studies with in-situ activity assessment based on stable isotope probing particularly in complex matrices of different terrestrial and marine environments. PAH degradation under various conditions of bioavailability will be assessed as to improve rational exploitation of the catalytic properties of bacteria for the treatment and prevention of PAH pollution. We will generate a knowledge base not only on the microbial catabolome for biodegradation of PAHs in various impacted environmental settings based on genome gazing, retrieval and characterization of specific enzymes but also on systems related bioavailability of contaminant mixtures. MAGICPAH takes into account the tremendous undiscovered meta-genomic resources by the direct retrieval from genome/meta-genome libraries and consequent characterization of enzymes through activity screens. These screens will include a high-end functional small-molecule fluorescence screening platform and will allow us to directly access novel metabolic reactions followed by their rational exploitation for bio-catalysis and the re-construction of biodegradation networks. Results from (meta-) genomic approaches will be correlated with microbial in situ activity assessments, specifically dedicated to identifying key players and key reactions involved in anaerobic PAH metabolism. Key processes for PAH metabolism particularly in marine and composting environments and the kinetics of aerobic degradation of PAH under different conditions of bioavailability will be assessed in model systems, the rational manipulation of which will allow us to deduce correlations between system performance and genomic blueprint. The results will be used to improve treatments of PAH-contaminated sites.
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