Steroid hormones are essential in orchestrating oocyte maturation, i.e. estrogens of follicular origin support the development of the female gamete and fertilization. In this project the concentration of free and conjugated estrogens during follicular development will be analysed and compared to local concentrations in the developing follicle. Cattle are suitable animal models because of the accessibility and suitability for frequent examination and sampling. Furthermore, it has been useful for understanding several features of human reproduction including follicular dynamics, the fate of the emerging follicles is orchestrated mainly by gonadotropins and steroid hormones in a similar manner. Ovarian SULT1E1 participates locally in the regulation of follicular estrogen activity. The ESTcatalysed down-regulation of estrogen activity enables normal ovulation. Conversely, sulfoconjugated estrogens may also be precursors of the production of free estrogens depending on estrogen sulfatase (StS) acitivity. In mammals, follicular luteinisation/ovulation is triggered by a surge in LH and is characterised by numerous physical and biochemical changes, including the decreased production of estradiol (E2). This loss in E2 biosynthetic capacity has been explained by a marked decrease in the expression of key steroidogenic enzymes involved in the follicular production of active estrogens. However, little is known about the regulation of enzymes/proteins responsible for the inactivation and elimination of estrogens, as mediated for example by EST during this period.
Die auf den 1. Oktober 2008 in Kraft gesetzte revidierte Freisetzungsverordnung (FrSV) weist auch dem Kanton Aargau im Bereich der gebietsfremden Organismen (Neobiota) zahlreiche neue Aufgaben zu. Wir beraten und unterstützen den Kanton dabei, ein Strategiepapier zu entwickeln, das die Leitlinien für den künftigen Umgang mit Neobiota definiert und eine zweckmäßige Organisation sowie die zugehörigen Abläufe festlegt. Ferner werden Sofortmassnahmen vorgeschlagen und die Aktivitäten der kommenden Jahre grob skizziert. Die Neobiota-Strategie des Kantons Aargau bezweckt, schädliche Auswirkungen von gebietsfremden Arten auf die Lebensqualität von Mensch und Tier, die wirtschaftlichen Aktivitäten sowie die Ökosysteme zu minimieren.
The Tropical Glaciology Group's research on Kilimanjaro started in 2002 and is in progress. Central aspects of our research plan are: 1) Development of the working hypothesis: From a synopsis of (i) proxy data indicating changes in East African climate since ca. 1850, (ii) 20th century instrumental data (temperature and precipitation), and (iii) the observations and interpretations made during two periods of fieldwork (June 2001 and July 2002) a scenario of modern glacier retreat on Kibo is reconstructed. This scenario offers the working hypothesis for our project. 2) Impact of local climate on the glaciers: This goal involves micrometeorological measurements on the glaciers, and the application of collected data to full glacier energy and mass balance models. These models quantify the impact of local climate on a glacier, based on pure physical system knowledge. Our models are validated by measured mass loss and surface temperature. 3) Latest Extent of the Kilimanjaro glaciers: Here, a satellite image was analyzed to derive the surface area and spatial distribution of glaciers on Kilimanjaro in February 2003. To validate this approach, an aerial flight was conducted in July 2005. 4) Linking local climate to large-scale circulation: As glacier behavior on Kilimanjaro, a totally free-standing mountain, is likely to reflect changes in larger-scale climate, this goal explores the large-scale climate mechanisms driving local Kilimanjaro climate. Well known large-scale forcings of east African climate are sea surface temperature variations in the Pacific and, more important, in the Indian Ocean. 5) Regional modification of large-scale circulation: The regional precipitation response in East Africa due to large-scale forcing is not adequately resolved in a global climate model as used in 4). Thus, mesoscale model experiments with the numerical atmospheric model RAMS will be conducted within this goal. They are thought to reveal the modification of atmospheric flow by the Kilimanjaro massif on a regional scale. 6) Practical aspects: Based on micro- and mesoscale results, (i) how much water is provided by glaciers, (ii) providing future projections of glacier behavior as basis for economic and societal studies (practical part), e.g., for studies on the impact of vanishing glaciers on Kibo's touristic appeal, and (iii) which impact does deforestation on the Kilimanjaro slopes have on summit climate? Referring to item 2), two new automatic weather stations have been installed in February 2005. They complete a station operated by Massachusetts University on the surface of the Northern Icefield since 2000.
Irrigation in the Yanqi Basin, Sinkiang, China has led to water table rise and soil salination. A model is used to assess management options. These include more irrigation with groundwater, water saving irrigation techniques and others. The model relies on input data from remote sensing.The Yanqi Basin is located in the north-western Chinese province of Xinjiang.This agriculturally highly productive region is heavily irrigated with water drawn from the Kaidu River. The Kaidu River itself is mainly fed by snow and glacier melt from the Tian Mountain surrounding the basin. A very poor drainage system and an overexploitation of surface water have lead to a series of environmental problems: 1. Seepage water under irrigated fields has raised the groundwater table during the last years, causing strongly increased groundwater evaporation. The salt dissolved in the groundwater accumulates at the soil surface as the groundwater evaporates. This soil salinization leads to degradation of vegetation as well as to a loss of arable farmland. 2. The runoff from the Bostan Lake to the downstream Corridor is limited since large amount of water is used for irrigation in the Yanqi Basin. Nowadays, the runoff is maintained by pumping water from the lake to the river. The environmental and ecological system is facing a serious threat.In order to improve the situation in the Yanqi Basin, a jointly funded cooperation has been set up by the Institute of Environmental Engineering, Swiss Federal Institute of Technology (ETH) , China Institute of Geological and Environmental Monitoring (CIGEM) and Xinjiang Agricultural University. The situation could in principle be improved by using groundwater for irrigation, thus lowering the groundwater table and saving unproductive evaporation. However, this is associated with higher cost as groundwater has to be pumped. The major decision variable to steer the system into a desirable state is thus the ratio of irrigation water pumped from the aquifer and irrigation water drawn from the river. The basis to evaluate the ideal ratio between river and groundwater - applied to irrigation - will be a groundwater model combined with models describing the processes of the unsaturated zone. The project will focus on the following aspects of research: (...)
Der WebFeatureService (WFS) stellt die gemeldeten "Online-Anliegen" der Bürger und Unternehmen, wie z.B. Schlaglöcher oder beschädigte Verkehrslichter, im Melde-Michel dar. Zur genaueren Beschreibung der Daten und Datenverantwortung nutzen Sie bitte den Verweis zur Datensatzbeschreibung.
Die Mängelmeldungen der Bürger und Unternehmen wie z.B. Schlaglöcher oder beschädigte Verkehrszeichen werden in einer Datenbank gespeichert und bereitgestellt und im Melde-Michel sichtbar dargestellt.
Die landesweite Waldzustandserhebung wird jährlich im bundesweiten Stichprobennetz (16x16 km) und nach einer abgestimmten Methodik durchgeführt. In Thüringen wurde das Stichprobennetz auf 4x4 km verdichtet, um flächenrepräsentative Aussagen für die Hauptbaumarten zu erhalten. Ziel der Waldzustandserhebung ist die langfristige Überwachung des Waldzustandes unter dem Einfluss abiotischer Einflüsse (z.B. Klima/Witterung, Luftschadstoffe) und biotischer Faktoren (z.B. Insektenkalamitäten). Der jährliche Waldzustandsbericht für Thüringen ist unter www.tmil.info zu finden.
Der Melde-Michel stellt in der Freien und Hansestadt Hamburg einen Mängelmeldedienst für Bürger und Unternehmen im Rahmen einer Webanwendung zur Verfügung. Die Meldung von Mängeln ist ebenfalls telefonisch über den Telefonischen HamburgService (Telefonnummer 115) möglich. Hierbei werden Infrastruktur-Mängel z. B. Schlaglöcher, beschädigte Verkehrslichter, Schäden beim städtischen Grün und mehr auf einfache Weise an die jeweils zuständige Dienststelle oder das jeweils beauftragte Unternehmen übermittelt. Bei der Nutzung via Smartphone kann die Lokalisierung mittels Standortermittlung erfolgen. Zusätzlich zur auszuwählenden Schaden-Kategorie können optional weitere Informationen, z.B. Beschreibung, Kontaktdaten und Fotos mitgegeben werden.
Cherry leaf roll virus (CLRV) is a plant pathogen of economic and ecologic importance. It is globally distributed in a wide range of forest, fruit, and ornamental trees and shrubs. In several areas of cherry and walnut production CLRV causes severe losses in yield and quality. With current reference to the rapid dissemination and strong symptom expression in Finnish birches and the Germany-wide distribution of CLRV in birches and elderberry, we continuously investigate and gradually reveal CLRV transmission pathways as by pollen, seeds or water. However, modes and interactions responsible for the wide intergeneric host transmission as well as for the exceptional CLRV epidemic in Fennoscandia still remain unknown. In this project systematic studies shall investigate biological vectors as a causal agent to finally derive control mechanisms and strategies to avoid new epidemics in different hosts and geographic regions. Detailed monitoring of the invertebrate fauna of birch stands/forests and elderberry plantations in Germany and Finland shall reveal potential vectors to subsequently study them in detail by approved virus detection methods and transmission experiments. Molecular analyses of the CLRV coat protein shall prove its role as a viral determinant for a virus/vector interaction. Consequently, this project essentially will contribute important answers on the CLRV epidemiology, and this will be a key element within the first network of research on plant viral pathogens in forest trees.
In today's biodiversity crisis, there is an urgent need to monitor terrestrial and aquatic species in their natural habitats, especially those that may be endangered, invasive or elusive. Traditional species observation methods, based on acoustic or observational surveys are inefficient, costly and time consuming. On the other hand, DNA is continuously deposited in the environment from natural processes and this environmental DNA (eDNA) allows us to detect species and reconstruct their communities with a high level of sensitivity. These data can be used to obtain occurrence records and to collect more population information in field. Crucially, these data are necessary to inform management agencies about the current state of our biodiversity, and are especially urgent for species that are currently data deficient. The aims of this study are to firstly identify occurrence records from diverse sources (databases, literature) and generate a database of distributional data for species of crustacean and mollusks that are data deficient in Sweden. Secondly, we aim to detect threatened species in Swedish marine, freshwater and terrestrial habitats using novel genomic methods (DNA metabarcoding, ddPCR). Finally, based on the new data, we will run species distribution and population models, to improve information on geographic range and population status for threatened invertebrates. The results will be integrated into current monitoring programmes (e.g. red-listing) and action plans.
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